HISTOMORPHOLOGICAL CHANGES IN ORGANS AND TISSUES OF GUINEA PIGS INFECTED WITH ENTEROTOXIGENIC STRAINS OF Y. ENTEROCOLITICA

Abstract

The results of the study of histomorphological changes in organs and tissues of guinea pigs infected with enterotoxigenic strains of Y. enterocolitica were presented. We established, in particular, the most affected in small intestine, where superficial necrotic enteritis was determined. Toxins are causative agent, getting into the bloodstream cause degenerative changes in the liver and pancreas. And also serous ecstracapillary glomerulonephritis and degenerated changes of epithelial tubules of the kidneys and serous myocarditis were caused. The infecting of guinea pigs leads significant activation of immune organs: thymus, spleen, somatic and visceral lymph nodes.