Change of areas of hair cuticle in sleep cats for nephropathy and polyorganic pathology

Abstract

89 males and females of domestic cats, aged 2.5–10.0 years, were examined. It was established that under different variants of nephropathy and for the development of hepatic and renal hepatic syndromes in domestic cats in the liver and kidneys there are significant structural changes that is reflected in the disturbances of metabolic processes determined by the results of clinical and microscopic and biochemical studies of blood serum, as well as changes in the area of hair cuticle (AHC) of the wool cover of cats. The study of the cuticle was carried out using negative impressions on a nitrocellulose lacquer, which was applied to the slide glass. Hair was removed from him after lacquering. The resulting imprint was analyzed under Carl Zeiss Jena microscope (Ч 400) and set the AHC in the root zone and in the thickest part of the rod, expressing the result in nm². In 40 % of clinically healthy cats, the size of the hair cuticle (AHC) is 8–9x10⁴ nm²; in 60 % of animals – 10–17x10⁴ nm². Such a significant spread of indicators is due to different age of animals and the influence of the rock factor. It turned out that 100 % of clinically healthy cats do not have the values of AHC 6–7´10⁴ nm². The higher the AHC  (13х10⁴ nm² or higher), the less likely an animal is the shelter or the initial form of kidney disease, and there is not one-hundred percent polyorganic hepatic-renal or renal-hepatic pathology. For acute renal failure, AHC values are predominantly in the range of values 13–14´10⁴ nm², that is, they do not differ from the norm. For chronic renal insufficiency, the value of AHC is 6–10´10⁴ nm². In general, for kidney diseases, there are no AHC higher than 15 nm². In polyorganic pathology in the form of hepatic-renal and renal-hepatic AHC syndromes in domestic cats, they are 6–12x10⁴ nm² and are not completely found outside the given range. In combination with the results of clinical and biochemical studies of blood serum, this technique allows differentiating syndromes depending on the primary link of the pathogenetic chain. It can be used for the dispensary examination of domestic cats, as well as for the study of the animals’ health of other species in normal and in pathology.