The effect of eimeriostatics on the morphological indicators of the blood of piglets with a mixed course of isosporosis and cryptosporidiosis

Abstract

Intestinal parasites have a significant impact on the efficiency of pig farming. Protozoa are a particular danger for young animals, as they can cause diarrhea and dehydration, which can lead to the death of the animals. Among the many pathogens that cause diarrhea in suckling piglets, the leading role is played by Isospora suis, Eimeria spp. and Cryptosporidium spp. Most parasites are capable of suppressing the host's immune system. In chronic parasitic diseases, the hematopoietic, antioxidant, and immune systems are primarily affected. Control of the effectiveness of eimeriostatics for the mixed course of isosporosis and cryptosporosis in piglets was carried out by morphological indicators of blood. The use of Turil 5 %, Brovitacoccide and Amprolev-plus leads to a tendency to improve the body's condition, which is confirmed by changes in the morphological composition of piglets' blood. However, the most pronounced changes and in the shortest time (on the 14th day of treatment) were observed in animals treated with the drug Amprolev-plus. The hemoglobin content increased by 7.2 %, the number of leukocytes decreased by 19.3 %, rod-shaped neutrophils – by 42.3 %, segmented neutrophils – by 16.4 %. Prior to treatment, lymphopenia, i.e., an immunodeficient state, was registered in the infected piglets from the experimental groups. The increase in the number of lymphocytes by 9.1 % occurred due to the content of the immunostimulant in the preparation. After the application of Turil 5 % and Brovitacoccide, the restoration of morphological indicators was registered only on the 28th day. The hemoglobin content increased by 9.7 % and 8.3 %, respectively, the number of leukocytes decreased by 15.3 % and 20.6 %, rod-shaped neutrophils – by 37.0 % and 42.3 %, segmented neutrophils – by 11.5 % and 16.1 %. The use of eimeriostatics in piglets affected by isosporosis (caused by Isospora suis) and cryptosporidiosis (caused by Cryptosporidium spp.) has a significant effect on their blood parameters and helps to control the disease. They are used to control and reduce the parasite load, thereby alleviating the clinical symptoms of the disease.