Physiological status in dogs when using Poltava bischofite solution of parvovirus enteritis

Abstract

The state of the organism, dynamics of indices of blood in dogs with parvovirus enteritis, schemes of
physiological status restoration have been studied in the paper. The natural ecologically clean remedy i.e.
Poltava bischofite solution (PBS) has been used for dogs for the first time. The treatment of the control group
animals included standard therapeutic pattern (0.9 % sodium chloride, Ringer's solution, Duphalyte,
Metronidazole, Ascorbic acid, Metoclopramide, Ethamsilate, Anfluron, Immunofan, Dexa-kel, Aminovit,
Vitazal, Amoxicillin); the standard pattern for the dogs of the experimental group has additionally included
2 % PBS at a dose of 1 ml/kg orally per 5 days. The clinical studies conducted of animals. Before treatment and
after recovery the animal's blood was drawn for hematological and biochemical analysis. The physiological
status of the dogs at the beginning of the study was unsatisfactory. Refusal of food and water, lethargy, a sharp
decrease in body weight, dry skin, disorders of the gastrointestinal tract, rarely the cardiovascular and
respiratory systems was observed. The body temperature at the beginning of the clinical manifestations
increased to 40.5±0.1 ºC. Diagnostic studies of sick animals revealed the decrease of leukocytes, stab and
segmented neutrophils, the increase of lymphocytes and monocytes as well as ESR, and the increase in ALT
and AST. On the 4th day of research the number of leukocytes in the blood increased among all animal the
experimental group by 8,0 %, which is higher than in the control group by 6,3 %. The percentage of stab
neutrophils increases in dogs of the control group by 59,1 %, the experimental group by 68,2 % which is
higher than in the control group by 39,7 %. The percentage of stab neutrophils increases in dogs of the control
group by The percentage of segmental neutrophils increases in dogs control and the experimental group on one
level. The increase in the number of neutrophilic forms of granulocytes is compensated by a decrease in
agranulocytes - lymphocytes and monocytes. In dogs of the experimental group with the use of PBS,
hemoglobin level increased by 19,2 %, which is 22,9 % higher than the control group. In animals experimental
group there is a decrease in ESR by 33,5 %. In recovered animals there is a decrease in ESR. Studies of blood
biochemical parameters have shown that in animals of all groups after recovery total protein, alkaline
phosphatase, ALT, AST, amylase, creatinine, urea and glucose are within physiological normal limits. It is
clarified that the proposed treatment method of dogs with the use of PBS with parvovirus enteritis have shown
the 100 % efficiency and fast of recovery of animals, which was confirmed by hematological and biochemical
studies of the physiological status state restoration of the organism.