HAEMATOLOGICAL AND BIOCHEMICAL INDICES OF BLOOD IN CATS WITH FELINE PANLEUKOPENIA WHEN USING POLTAVA BISCHOFITE SOLUTION

Abstract

The haematological and biochemical indices of blood in cats with feline panleukopenia, age peculiarities of susceptibility to the disease and seasonality, schemes of physiological status restoration have been studied in the paper. The natural ecologically clean remedy i.e. Poltava bischofite solution (PBS) has been used for cats for the first time. The treatment of the control group animals included standard therapeutic pattern; the standard pattern for the cats of the 1st experimental group has been improved with antibacterial, vitamin and immunostimulating drugs, and the standard pattern of the 2nd experimental group has additionally included 2 % PBS at a dose of 1 ml/kg orally per 5 days. Before treatment and after recovery the animal's blood was drawn for hematological and biochemical analysis. Diagnostic studies of sick animals revealed the decrease of leukocytes, stab and segmented neutrophils, the increase of lymphocytes as well as ESR, the decrease in alkaline phosphatase, and the increase in ALT and AST. After recovery the number of leukocytes in the blood significantly (p<0.05) increased among all animal groups: control group – by 13.1 %, the 1st experimental group – by 54.4 %, the 2nd experimental group with the use of PBS – by 67.8 %. The percentage of stab neutrophils increases in cats of the control group by 3.75 times (p<0.001); 1st experimental group – 3.1 times (p<0,001); 2nd experimental group – 5.0 times (p<0.001), which is significantly higher (p<0.01) than in the control group by 66.7 %. The percentage of segmental neutrophils increases in control animals by 1.07 times; 1st experimental group – 1.38 times; 2nd experimental group – significantly (p<0.05) 1.51 times. The increase in the number of neutrophilic forms of granulocytes is compensated by a decrease in agranulocytes - lymphocytes and monocytes. In recovered animals of all groups there is a decrease in ESR. In cats of the 2nd experimental group with the use of PBS the number of erythrocytes increased by 32.2 %, which is 24.2 % higher than the control group, hemoglobin level by 19.3 %, which is higher than the control group by 17.3 %. Studies of blood biochemical parameters have shown that in animals of all groups after recovery total protein, alkaline phosphatase, ALT, AST, amylase, creatinine, urea and glucose are within normal limits. The liver intoxication indices were the lowest in the 2nd experimental group with the use of PBS while they were the highest of the control group. The proposed treatment methods of cats with feline panleukopenia have shown high efficiency, which was confirmed by hematological and biochemical studies of the physiological state of the organism. The best result has been shown by the treatment pattern with PBS.