Phenotypic and morphological changes of pancreas cells culture of rats during cultivation

Abstract

The research of primary culture of rat’s pancreas cells showed that it is morphologically heterogeneous, inter the dominant fibroblast-like cells we observed a small amount of polygonal. Starting from the second passage culture became the homogeneous by fibroblast-like cells. Immunophenotyping population of cell culture is derived from rat pancreas, revealed a high level of expression of CD38, moderate level – CD66e, CD95, CD326, low level – CD227, lack of expression – CD10, CD34, CD45, CD48, CD54, CD56, pankeratin.